Upstream Bio Inc (UPB)

Currency in USD
10.49
+0.07(+0.67%)
Closed·
10.80+0.31(+2.96%)
·
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Fair Value
Day's Range
10.3410.67
52 wk Range
7.2233.68
Key Statistics
Prev. Close
10.42
Open
10.48
Day's Range
10.34-10.67
52 wk Range
7.22-33.68
Volume
733.34K
Average Volume (3m)
1.31M
1-Year Change
42.3338%
Book Value / Share
6.29
Fair Value
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Fair Value Upside
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UPB Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
43.57
Upside
+315.36%
Members' Sentiments
Bearish
Bullish
ProTips
3 analysts have revised their earnings upwards for the upcoming period

Upstream Bio Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Buy
Technical Indicators
Strong Buy
Moving Averages
Strong Buy

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.

Compare UPB to Peers and Sector

Metrics to compare
UPB
Peers
Sector
Relationship
P/E Ratio
−4.0x−6.5x−0.4x
PEG Ratio
−0.08−0.330.00
Price/Book
1.7x6.0x2.6x
Price / LTM Sales
200.0x7.9x3.2x
Upside (Analyst Target)
309.9%55.4%50.9%
Fair Value Upside
Unlock16.9%6.8%Unlock

Analyst Ratings

7 Buy
1 Hold
0 Sell
Ratings:
8 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 43.57
(+315.36% Upside)
Firm
ArticlePositionPrice TargetUpside / DownsideFrom Price TargetActionDate
Truist Securities
Buy43.00+309.91%47.00MaintainApr 02, 2026
Evercore ISI
Hold15.00+42.99%40.00DowngradeMar 27, 2026
TD Cowen
Buy---MaintainFeb 11, 2026
TD Cowen
Buy---MaintainFeb 05, 2026
Mizuho
Buy51.00+386.18%-New CoverageDec 19, 2025

Earnings

Latest Release
Mar 26, 2026
EPS / Forecast
-0.78 / -0.84
Revenue / Forecast
668K / --
EPS Revisions
Last 90 days

UPB Income Statement

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FAQ

What Is the Upstream Bio (UPB) Stock Price Today?

The Upstream Bio stock price today is 10.49 USD.

What Stock Exchange Does Upstream Bio Trade On?

Upstream Bio is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Upstream Bio?

The stock symbol for Upstream Bio is "UPB."

What Is the Upstream Bio Market Cap?

As of today, Upstream Bio market cap is 570.87M USD.

What Is Upstream Bio's Earnings Per Share (TTM)?

The Upstream Bio EPS (TTM) is -2.66.

When Is the Next Upstream Bio Earnings Date?

Upstream Bio will release its next earnings report on May 12, 2026.

From a Technical Analysis Perspective, Is UPB a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Buy.

How Many Times Has Upstream Bio Stock Split?

Upstream Bio has split 0 times.

How Many Employees Does Upstream Bio Have?

Upstream Bio has 75 employees.

What is the current trading status of Upstream Bio (UPB)?

As of Apr 11, 2026, Upstream Bio (UPB) is trading at a price of 10.49 USD, with a previous close of 10.42 USD. The stock has fluctuated within a day range of 10.34 USD to 10.67 USD, while its 52-week range spans from 7.22 USD to 33.68 USD.

What Is Upstream Bio (UPB) Price Target According to Analysts?

The average 12-month price target for Upstream Bio is 43.57 USD, with a high estimate of 75 USD and a low estimate of 15 USD. 7 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Strong Buy. The stock has an +315.36% Upside potential.

What Is the UPB Premarket Price?

UPB's last pre-market stock price is 10.32 USD. The pre-market share volume is 560.00, and the stock has decreased by -0.10, or -0.96%.

What Is the UPB After Hours Price?

UPB's last after hours stock price is 10.80 USD, the stock has decreased by 0.31, or 2.96%.
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