Spero Therapeutics Inc (SPRO)

Currency in USD
1.190
-0.040(-3.25%)
Real-time Data·
SPRO is not included in our AI-picked strategies. See which stocks are.
Fair Value
Day's Range
1.1901.240
52 wk Range
1.0803.080
Key Statistics
Prev. Close
1.23
Open
1.21
Day's Range
1.19-1.24
52 wk Range
1.08-3.08
Volume
109.98K
Average Volume (3m)
1.6M
1-Year Change
-37.6963%
Book Value / Share
0.76
Fair Value
unlockUnlock
Fair Value Upside
unlockUnlock
SPRO Scorecardpro icon
Company’s Health
Unlock
Fair Value
Unlock Price
Fair Price
Upside
Price Target
4.000
Upside
+236.13%
Members' Sentiments
Bearish
Bullish
ProTips
RSI suggests the stock is in oversold territory

Spero Therapeutics Inc News & Analysis

Show more

Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Strong Sell

Analyst Ratings

0 Buy
1 Hold
0 Sell
Ratings:
1 analysts
Overall Consensus
Neutral

Analysts 12-Month Price Target:

Average 4.000
(+236.13% Upside)

Spero Therapeutics Inc Earnings Call Summary for Q2/2026

  • Spero posted Q2 2026 adjusted loss of $0.16/share, beating consensus estimate of $0.17, though revenue fell to $0 from $14.2M year-over-year.
  • Company secured $105M royalty financing in July, extending cash runway into H2 2029 to fund operations and $35M upfront payment for SP001 license.
  • FDA approved Utebzi oral carbapenem in June; GSK partner expected to launch product to U.S. patients in H2 2026, generating future royalties.
  • Strategic pivot to immunology announced, centering on SP001 CD40 ligand antibody with Phase II trial in IgG4-related disease planned for Q2 2027.
  • Net loss widened to $9.6M from $1.7M year-over-year despite 68% R&D cost reduction; shares fell 3.25% to $1.19, recovering 2.53% after hours.
Last Updated: 08/13/2026, 05:40 AM
Read Full Transcript

Earnings

Latest Release
Aug 12, 2026
EPS / Forecast
-0.16 / -0.17
Revenue / Forecast
-- / --
EPS Revisions
Last 90 days

SPRO Income Statement

Compare SPRO to Peers and Sector

Metrics to compare
SPRO
Peers
Sector
Relationship
P/E Ratio
9.6x5.6x−0.4x
PEG Ratio
0.09−0.200.00
Price/Book
1.6x3.1x2.6x
Price / LTM Sales
1.5x75.8x3.1x
Upside (Analyst Target)
225.2%128.1%47.9%
Fair Value Upside
Unlock19.3%6.3%Unlock

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company’s product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

Ownership

Ownership Overview

Type
Common Stock Held% of Shares OutstandingMarket Value
Mutual Funds & ETFs
3.43M5.92%4.22M
Other Institutional Investors
17.61M30.41%21.66M
Public Companies & Retail Investors
36.86M63.67%45.34M
Total
57.9M100.00%71.22M

Top Holders

Holder
% of holding
Shares Held
Date Reported
Value (In 1,000s)
GSK Equity Investments, Limited15.87%9,190,60611,304
Pfizer Venture Investments LLC4.08%2,362,3482,906

People Also Watch

8.3900
ASTC
-0.24%
253.38
CBRS
+15.71%
0.722
OTLK
-4.53%
4.005
RXT
-4.87%
147.97
SPCX
+5.69%

FAQ

What Is the Spero Therapeutics (SPRO) Stock Price Today?

The Spero Therapeutics stock price today is 1.190 USD.

What Stock Exchange Does Spero Therapeutics Trade On?

Spero Therapeutics is listed and trades on the Nasdaq Stock Exchange.

What Is the Stock Symbol for Spero Therapeutics?

The stock symbol for Spero Therapeutics is "SPRO."

What Is the Spero Therapeutics Market Cap?

As of today, Spero Therapeutics market cap is 69.590M USD.

What Is Spero Therapeutics's Earnings Per Share (TTM)?

The Spero Therapeutics EPS (TTM) is 0.129.

When Is the Next Spero Therapeutics Earnings Date?

Spero Therapeutics will release its next earnings report on Nov 16, 2026.

From a Technical Analysis Perspective, Is SPRO a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

How Many Times Has Spero Therapeutics Stock Split?

Spero Therapeutics has split 0 times.

How Many Employees Does Spero Therapeutics Have?

Spero Therapeutics has 25 employees.

What is the current trading status of Spero Therapeutics (SPRO)?

As of Aug 17, 2026, Spero Therapeutics (SPRO) is trading at a price of 1.190 USD, with a previous close of 1.230 USD. The stock has fluctuated within a day range of 1.190 USD to 1.240 USD, while its 52-week range spans from 1.080 USD to 3.080 USD.

What Is Spero Therapeutics (SPRO) Price Target According to Analysts?

The average 12-month price target for Spero Therapeutics is 4.000 USD, with a high estimate of 4 USD and a low estimate of 4 USD. 0 analysts recommend buying the stock, while 0 suggest selling, leading to an overall rating of Neutral. The stock has an +236.13% Upside potential.

What Is the SPRO Premarket Price?

SPRO's last pre-market stock price is 1.240 USD. The pre-market share volume is 1,960.000, and the stock has decreased by 0.010, or 0.810%.

What Is the SPRO After Hours Price?

SPRO's last after hours stock price is 1.270 USD, the stock has decreased by 0.040, or 3.250%.
Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers.
© 2007-2026 - Fusion Media Limited. All Rights Reserved.