ProQR Therapeutics N.V., a clinical-stage biotechnology company, focuses on the discovery and development of novel therapeutic medicines. The company develops an RNA editing platform through its Axiomer RNA editing technology for genetic disorders with unmet needs. Its lead product candidate, AX-0810, targets na-taurocholate cotransporting polypeptide (NTCP) for the treatment of cholestatic diseases. The company also develops AX-2402, which targets methyl CpG binding protein 2 mutations for Rett syndrome; AX-2911, which targets PNPLA3 for metabolic dysfunction-associated steatohepatitis; and AX-1412, which targets the B4GALT1 gene for cardiovascular diseases. It has a research and collaboration agreement with Eli Lilly and Company for the discovery, development, and commercialization of potential new medicines for genetic disorders in the liver and nervous system. The company was incorporated in 2012 and is headquartered in Leiden, the Netherlands.
RNA Editing Pionee | ProQR Therapeutics leads in RNA editing technology, targeting cholestatic diseases and MASH with its innovative Axiomer platform and expanding clinical pipeline |
Financial Stability | $143M cash position sustains operations until mid-2027, with analyst price targets ranging from $4 to $14, suggesting significant upside potential |
Strategic Partnerships | Collaboration with Eli Lilly bolsters credibility and valuation, while diverse pipeline across multiple therapeutic areas showcases platform versatility |
Clinical Milestones | AX-0810's Phase 1 trial initiation marks a crucial step, with data expected in Q4 2025 potentially validating the RNA editing approach and derisking the platform |
Metrics to compare | PRQR | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipPRQRPeersSector | |
|---|---|---|---|---|
P/E Ratio | −3.4x | −3.5x | −0.4x | |
PEG Ratio | 0.14 | −0.02 | 0.00 | |
Price/Book | 2.9x | 1.6x | 2.6x | |
Price / LTM Sales | 8.7x | 18.1x | 3.2x | |
Upside (Analyst Target) | - | 150.4% | 46.7% | |
Fair Value Upside | Unlock | 0.5% | 7.6% | Unlock |