MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics to treat cancer in the United States. The company’s product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resistant ovarian cancer and clear cell gynecologic cancer which has completed phase 1 clinical trial; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload; MGC028, an antibody-drug conjugates (ADC) that targets ADAM9 and delivers a novel TOP1i-based linker-payload for the treatment of solid tumors, which is in phase 1 clinical trials; MGC030, a ADC molecule for the treatment of solid tumors, which is in preclinical trials. It is also developing next generation T-cell engager programs. The company has collaborations with TerSera Therapeutics LLC; Incyte Corporation; and Gilead Sciences, Inc. MacroGenics, Inc. was incorporated in 2000 and is headquartered in Rockville, Maryland.
Pipeline Progress | Explore MacroGenics' evolving pipeline, featuring promising candidates like lorigerlimab and MGC026, as the company pivots from discontinued programs to new opportunities |
Financial Fortification | Delve into MacroGenics' strategic moves, including a $70M royalty agreement, extending cash runway to 2027 and bolstering its position for future growth |
Catalysts on Horizon | Uncover critical upcoming events for MacroGenics, including Phase 2 data readouts and potential partnerships, that could significantly impact company valuation |
Market Valuation | Analyst price targets range from $2 to $8 per share, reflecting diverse perspectives on MacroGenics' potential in a competitive biotech landscape |
Metrics to compare | MGNX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipMGNXPeersSector | |
|---|---|---|---|---|
P/E Ratio | −1.3x | −2.1x | −0.6x | |
PEG Ratio | −0.06 | 0.08 | 0.00 | |
Price/Book | 1.5x | 3.7x | 2.6x | |
Price / LTM Sales | 0.8x | 9.5x | 3.2x | |
Upside (Analyst Target) | 87.5% | 67.0% | 41.8% | |
Fair Value Upside | Unlock | 3.1% | 5.1% | Unlock |