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Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. The company’s products in pipeline includes Plozasiran, which is in Phase 2b and one Phase 3 clinical trial to treat hypertriglyceridemia, mixed dyslipidemia, and chylomicronemia syndrome; Zodasiran that is in Phase 2b clinical trial for the treatment of dyslipidemia and hypertriglyceridemia; ARO-PNPLA3, which is in Phase 1 clinical trial to treat patients with non-alcoholic steatohepatitis; ARO-RAGE that is in Phase 1/2a clinical trial to treat inflammatory pulmonary conditions; and ARO-MUC5AC, which is in Phase 1/2a clinical trial to treat muco-obstructive pulmonary diseases. It also develops ARO-MMP7 that is in Phase 1/2a clinical trial for treatment of idiopathic pulmonary fibrosis; ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-SOD1 for the potential treatment of amyotrophic lateral sclerosis; and ARO-C3, which is in Phase 1/2a clinical trial for the treatment of patients with various complement mediated or complement associated renal diseases. In addition, the company is involved in the development of JNJ-3989, which is in Phase 2 clinical trial to treat chronic hepatitis B virus infection; Olpasiran that is in Phase 3 clinical trial to reduce the production of apolipoprotein A; GSK-4532990 that is in phase 2 clinical trial to treat liver diseases; HZN-457, which is in phase 1 clinical trial to treat uncontrolled gout; and Fazirsiran that is in Phase 3 clinical trial for the treatment for liver disease associated with alpha-1 antitrypsin deficiency. Arrowhead Pharmaceuticals, Inc. has license and research collaboration agreements with Janssen Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; Horizon Therapeutics Ireland DAC; Amgen Inc.; and Glaxosmithkline Intellectual Property (No. 3) Limited. The company was founded in 2003 and is headquartered in Pasadena, California.
Name | Age | Since | Title |
---|---|---|---|
Douglass B. Given | 69 | 2010 | Chairman of the Board |
Christopher R. Anzalone | 52 | 2007 | CEO, President & Director |
Robert G. Gish | - | - | Chairman of Hepatitis B Clinical Advisory Board |
William D. Waddill | 65 | 2018 | Independent Director |
Michael S. Perry | 64 | 2011 | Independent Lead Director |
Mauro Ferrari | 64 | 2008 | Independent Director |
Carlo Ferrari | - | - | Member of Hepatitis B Clinical Advisory Board |
Stephen Alister Locarnini | - | - | Member of Hepatitis B Clinical Advisory Board |
Ching-Lung Lai | - | - | Member of Hepatitis B Clinical Advisory Board |
Jeffrey H. Teckman | - | - | Member of Alpha-1 Antitrypsin Deficiency Clinical Advisory Board |
Johnson Y. N. Lau | - | - | Member of Hepatitis B Clinical Advisory Board |
James K. Stoller | - | - | Member of Alpha-1 Antitrypsin Deficiency Clinical Advisory Board |
Rohit Loomba | - | - | Member of Alpha-1 Antitrypsin Deficiency Clinical Advisory Board |
Victoria M. Vakiener | 59 | 2022 | Independent Director |
Adeoye Y. Olukotun | 78 | 2020 | Independent Director |
Mark M. Davis | - | - | Founder and Founder & Director of Insert Therapeutics Inc & Calando |
Hongbo Lu | 52 | 2024 | Independent Director |
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