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Piper Sandler sees blockbuster potential in Immatics stock due to PRAME portfolio

EditorEmilio Ghigini
Published 10/07/2024, 04:54 PM
IMTX
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On Monday, Immatics (NASDAQ:IMTX), a clinical-stage biopharmaceutical company, received a new Overweight rating from Piper Sandler, accompanied by a bullish price target of $19.00 on the stock.

The firm based its optimistic outlook on the company's platform, especially its PRAME-targeting portfolio, which is believed to have extensive applicability across various solid tumors.

Piper Sandler highlighted the potential of Immatics' IMA203 as a leading cell therapy candidate for post-PD-1 melanoma. The firm's scenario modeling suggests a competitive durability profile that could pave the way for the program's registrational development. The analyst noted that this could position IMA203 favorably in the market.

The firm also identified significant opportunities for Immatics beyond melanoma, particularly with IMA203CD8, which is expected to show meaningful clinical activity in ovarian, endometrial, and lung cancers. According to the coverage initiation, there are numerous data points that support the firm's confidence in the clinical outcomes for these cancers.

Piper Sandler's analysis points to Immatics possessing a potential blockbuster cell therapy portfolio. The firm anticipates a series of data releases over the next 6-18 months, which are expected to further de-risk the company's portfolio and offer validation for the therapies in development.

The new price target of $19.00 reflects a substantial increase from the current trading levels, indicating a strong vote of confidence in the future performance of Immatics' stock. Investors responded positively to the news, with shares of Immatics likely to be influenced by the expectations set forth by Piper Sandler's coverage initiation.

In other recent news, Immatics has been active in the biopharmaceutical sector, with both clinical developments and executive appointments. The company retained its Outperform rating from Mizuho, with no change in the target price of $16.00.

This affirmation followed the presentation of updated Phase 1 data at the European Society for Medical Oncology and the return of the IMA401 program from partner Bristol Myers (NYSE:BMY) Squibb.

The Phase 1 data for the therapeutic candidate, IMA401, was presented, marking the first clinical results for Immatics' TCR bispecific efforts. Although the overall response rate for IMA401 wasn't disclosed, the disease control rate was reported at 55%, a metric Mizuho considers a promising indicator of efficacy for TCR-based therapies.

In addition, Immatics has appointed Dr. Alise Reicin to its Board of Directors, a move expected to bring valuable clinical and strategic expertise to the company as it advances its T cell-redirecting cancer immunotherapies. These recent developments show Immatics' continued efforts in advancing its TCR-based approach to treating solid tumors.

InvestingPro Insights

To complement Piper Sandler's optimistic outlook on Immatics (NASDAQ:IMTX), recent data from InvestingPro offers additional context for investors. Despite the company's promising pipeline and potential for blockbuster therapies, InvestingPro Tips highlight that Immatics is not currently profitable and does not pay a dividend to shareholders. This aligns with the typical profile of a clinical-stage biopharmaceutical company focusing on research and development.

Interestingly, InvestingPro data shows that Immatics has a market capitalization of $1.12 billion, reflecting investor confidence in its future potential. The company's revenue for the last twelve months as of Q2 2023 stood at $75.92 million, although it experienced a revenue decline of 16.48% during this period. This financial picture underscores the importance of the upcoming data releases mentioned in the article, which could significantly impact the company's valuation and market perception.

An InvestingPro Tip notes that Immatics holds more cash than debt on its balance sheet, which is crucial for a company in the capital-intensive biotech sector. This financial stability could provide the runway needed to advance its promising PRAME-targeting portfolio and other pipeline candidates.

For investors seeking a more comprehensive analysis, InvestingPro offers 6 additional tips for Immatics, providing a deeper understanding of the company's financial health and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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