🎈 Up Big Today: Find today's biggest gainers with our free screenerTry Stock Screener

Truist maintains hold on AnaptysBio with $30 target

Published 11/20/2024, 04:12 AM
ANAB
-

On Tuesday, Truist Securities maintained their Hold rating on shares of AnaptysBio (NASDAQ: NASDAQ:ANAB), with a steady price target of $30.00. The firm's assessment follows AnaptysBio's recent presentation at the American College of Rheumatology (ACR). The biotechnology company showcased a poster that indicated a positive correlation between synovial Programmed Death-1 (PD-1) expression and the severity of Rheumatoid Arthritis (RA), as measured by various biomarkers.

The data presented suggested that approximately 80% of T cells in the diseased synovium of RA patients express high levels of PD-1. This finding implies that PD-1 agonism, potentially through drugs like rosnilimab, could influence the progression of RA. However, Truist Securities noted that while the evidence is correlative, it does not significantly enhance their confidence in the ongoing Phase 2b RENOIR trial (NCT06041269), which is expected to report its topline data in February 2025.

The analyst from Truist Securities acknowledged the high standard for treatments in the RA market, referencing a list of drugs that are either approved or under development for the condition. The high efficacy bar in the RA space suggests that new treatments must demonstrate significant benefits to stand out in the competitive landscape.

AnaptysBio's research into the role of PD-1 in RA is part of the broader effort to develop effective treatments for the autoimmune disease, which continues to challenge patients and healthcare providers. With the RENOIR trial's results pending in the future, stakeholders and investors are closely watching the developments in AnaptysBio's pipeline for potential impact on the company's prospects.

In other recent news, AnaptysBio has seen a flurry of activity from analysts. Guggenheim reiterated its Buy rating, highlighting the potential of the company's BTLA agonist, ANB032, in treating autoimmune diseases. The firm also expressed confidence in the upcoming Phase IIb study results for ANB032, indicating potential in the expected $10 billion market post-dupilumab. Meanwhile, H.C. Wainwright reduced its price target for AnaptysBio due to an increase in operating expenses and a third-quarter operating loss of $22.8 million. However, the company reported a significant increase in collaboration revenue, rising to $30 million in the third quarter.

Leerink Partners trimmed their target price but maintained an Outperform rating due to AnaptysBio's robust portfolio. Piper Sandler also maintained an Overweight rating, noting the potential success of the ongoing Phase 2b ROSETTA study for rosnilimab, a PD-1 agonist, in patients with moderate to severe Ulcerative Colitis. AnaptysBio reported a third-quarter net loss of $32.9 million, with a cash and equivalents position of $458.0 million.

In clinical developments, AnaptysBio's ANB032 is advancing to a Phase 2b ARISE-AD trial, and rosnilimab is proceeding to a Phase 2b RENOIR RA trial. The company also reported positive results from the GEMINI-1 and GEMINI-2 Phase 3 trials for imsidolimab, a treatment for generalized pustular psoriasis. These are the recent developments in AnaptysBio's financial and clinical progress.

InvestingPro Insights

Recent InvestingPro data provides additional context to AnaptysBio's (NASDAQ: ANAB) current position as it advances its research in Rheumatoid Arthritis treatments. The company's market capitalization stands at $602.18 million, reflecting investor sentiment amidst ongoing clinical trials.

AnaptysBio's financial health shows mixed signals. While the company's revenue growth is impressive at 282.17% over the last twelve months, it's important to note that the company is not yet profitable, with a negative gross profit margin of -170.72%. This aligns with the biotech industry's typical profile of high research and development costs during drug development phases.

InvestingPro Tips highlight that analysts anticipate sales growth in the current year, which could be linked to the potential success of treatments like rosnilimab. Additionally, the stock's RSI suggests it may be in oversold territory, which could be of interest to value investors considering the company's pipeline potential.

It's worth noting that AnaptysBio's stock has experienced significant volatility, with a 46.03% decline over the past month. This volatility may reflect the market's reaction to ongoing clinical developments and the high-stakes nature of the RA treatment landscape discussed in the article.

For investors seeking a deeper understanding of AnaptysBio's prospects, InvestingPro offers 11 additional tips that could provide valuable insights into the company's financial health and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers.
© 2007-2024 - Fusion Media Limited. All Rights Reserved.