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Verastem Oncology appoints new CMO to lead cancer drug trials

EditorNatashya Angelica
Published 04/19/2024, 06:26 AM
VSTM
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BOSTON - Verastem Oncology (NASDAQ:VSTM), a biopharmaceutical company specializing in cancer treatments, announced today the appointment of Dr. John Hayslip as Chief Medical Officer (CMO). Dr. Hayslip brings over 25 years of oncology experience to the role, where he will oversee the clinical and medical strategy of the company, succeeding Dr. Louis J. Denis.

Dr. Hayslip's career spans various leadership positions, including his recent role as CMO at I-MAB Biopharma and Vice President of Clinical Development at Nektar Therapeutics (NASDAQ:NKTR). He has also held significant academic roles, such as Chief of Hematology and Bone Marrow Transplant at the University of Kentucky's Markey Cancer Center.

His academic credentials include a medical degree from Northeast Ohio Medical University and a master’s degree in clinical research from the Medical University of South Carolina.

In his new position at Verastem Oncology, Dr. Hayslip will lead the development programs for avutometinib, including the international confirmatory Phase 3 RAMP 301 clinical trial. The company is focused on addressing RAS/MAPK pathway-driven cancers, which include low-grade serous ovarian cancer, pancreatic cancer, and lung cancer.

Verastem Oncology is also planning a rolling New Drug Application (NDA) submission for the combination of avutometinib and defactinib in treating low-grade serous ovarian cancer within the first half of this year.

Dr. Hayslip expressed enthusiasm for his new role, highlighting the company's novel approach to targeting both the RAS signaling pathway and key mechanisms of resistance, aiming to improve outcomes for patients with RAS/MAPK pathway-driven cancers.

Verastem Oncology's pipeline includes novel small molecule drugs that inhibit critical signaling pathways in cancer cells, focusing on RAF/MEK inhibition and FAK inhibition.

This announcement comes with the usual forward-looking statements disclaimer, noting that the company's statements are subject to risks and uncertainties that could cause actual results to differ materially from those projected. These include the success of development and potential commercialization of product candidates, the timing and outcome of clinical trials, and regulatory approvals.

The information in this article is based on a press release statement from Verastem Oncology.

InvestingPro Insights

As Verastem Oncology (NASDAQ:VSTM) welcomes Dr. John Hayslip as the new Chief Medical Officer, it's worth noting the company's financial and market position, according to InvestingPro data. Verastem's market capitalization stands at $258.77 million, reflecting its current valuation within the biopharmaceutical sector. Despite a challenging market, the stock has experienced a significant 1-year price total return of 136.97%, showcasing a robust performance over the past year.

InvestingPro Tips highlight that Verastem holds more cash than debt on its balance sheet, which could provide financial flexibility as Dr. Hayslip steers the company's clinical and medical strategy. Additionally, with liquid assets surpassing short-term obligations, Verastem appears to be in a stable position to manage its immediate financial commitments. However, analysts have raised concerns as they do not anticipate the company will be profitable this year, and the stock has taken a hit over the last week with a -8.21% return. These factors may influence the company's strategic decisions and could be critical for investors to monitor.

For those seeking a deeper dive into Verastem Oncology's financial health and future prospects, InvestingPro offers a comprehensive set of additional tips, including metrics on profitability, gross profit margins, and price upticks. To access these insights and more, visit InvestingPro's Verastem page. Plus, use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription, unlocking an array of valuable investment tools and data.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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