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H.C. Wainwright lowers Rallybio shares target, sees potential in FNAIT treatment

EditorEmilio Ghigini
Published 08/12/2024, 07:20 PM
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On Monday, H.C. Wainwright adjusted its outlook on Rallybio Corp (NASDAQ:RLYB) shares, decreasing the 12-month price target to $6 from $9, while keeping a Buy rating on the stock. The firm's decision reflects new financial considerations following a reassessment of the company's operating expenses.

Rallybio is focused on developing treatments for rare disorders, including Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT), a condition where a mother's immune system attacks her baby's platelets, potentially leading to severe complications such as intracranial hemorrhage (ICH).

The firm's analyst highlighted the significance of RLYB112's Phase 1b proof-of-concept data, which demonstrated the molecule's potential in preventing FNAIT by rapidly clearing HPA-1a positive platelets from the circulation of HPA-1a negative healthy subjects.

The next major step for Rallybio is the initiation of a Phase 2 trial for RLYB212, which is expected to begin in the fourth quarter of 2024, having been narrowed down from the second half of the year. This upcoming trial will be particularly noteworthy as it will be the first to involve patients, specifically pregnant women at risk of FNAIT.

The firm underscored the absence of any FDA-approved therapy for FNAIT and suggested that, should RLYB212 prove effective, it could establish a new standard-of-care for the prevention of this rare immune disorder.

The analyst's optimism about the drug's potential is maintained despite the reduction in the price target, which was attributed to updated operational expense projections.

In other recent news, Rallybio Corporation announced an executive transition plan. Dr. Martin Mackay will resign from his Executive Chairman role by the end of 2024 but will continue to serve on Rallybio's Board of Directors. Following his resignation, he will assume the role of Chairman of the Board and will also work as a consultant for the company.

In addition to corporate changes, Rallybio has secured a strategic equity investment from Johnson & Johnson, which will support Rallybio's Phase 3 trial of nipocalimab for FNAIT treatment. The company has also announced a partnership with Johnson & Johnson to advance FNAIT treatments, involving a $6.6 million equity investment from Johnson & Johnson Innovation – JJDC, Inc.

Furthermore, Jones Trading maintained its Buy rating for Rallybio Corp, with a price target of $20. This follows Rallybio's announcement of an epidemiology analysis of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT), which suggests the condition may be more prevalent in at-risk pregnancies than previously understood. Rallybio is preparing for a Phase 2 trial of its prime asset, RLYB212, aimed at treating FNAIT.

On the other hand, JPMorgan has downgraded Rallybio's stock from Overweight to Neutral, citing a lack of near-term catalysts in 2024, but acknowledges the long-term value of Rallybio's RLYB212. Despite the downgrade, the firm still recognizes the inherent value in Rallybio's lead drug candidate for the future.

InvestingPro Insights

As Rallybio Corp (NASDAQ:RLYB) navigates through its clinical trials and operational developments, real-time data from InvestingPro offers a snapshot of the company's financial health and market performance. With a market cap of approximately $47.3 million, Rallybio is considered a small-cap company, which can be subject to higher volatility and risk compared to larger enterprises. The company's price-to-book ratio over the last twelve months as of Q2 2024 stands at 0.59, suggesting that the stock may be undervalued relative to its assets, which could attract value investors.

However, a concerning aspect revealed by InvestingPro is the company's significant operating loss of -$74.0 million over the same period, indicating challenges in achieving profitability in the near term. This is echoed in one of the InvestingPro Tips, noting that analysts do not expect Rallybio to be profitable this year. Additionally, with a price that has fallen by over 80% from its 52-week high, the stock appears to be trading near its lowest point in the past year, which aligns with another InvestingPro Tip highlighting the stock's recent poor performance.

For investors considering Rallybio as a potential investment, these insights can be crucial in understanding the risks and opportunities associated with the stock. It is worth noting that there are numerous additional InvestingPro Tips available for those seeking more in-depth analysis, which can be accessed for Rallybio Corp at https://www.investing.com/pro/RLYB.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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