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Celularity reports advances in cancer T-cell therapy

EditorNatashya Angelica
Published 06/03/2024, 11:54 PM
CELU
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FLORHAM PARK, N.J. - Celularity Inc. (NASDAQ: CELU), a biotechnology firm specializing in regenerative medicine, announced significant findings related to its T-cell therapy platform at the American Society of Clinical Oncology (ASCO) Annual Meeting held recently in Chicago. The company's preclinical asset, PT-CD16VS, demonstrated potent activity against multiple cancer types when combined with monoclonal antibodies.

This new data builds upon previous findings presented at the American Association for Cancer Research (AACR) in April, showcasing the potential of PT-CD16VS in targeting HER2-positive cancers. The latest results indicate a broader applicability across various hematological and solid tumors, suggesting a new avenue for addressing challenging cancers that are difficult to treat with conventional therapies.

Dr. Robert Hariri, CEO and Founder of Celularity, emphasized the significance of these findings. He stated that the data underscore the potential of leveraging the company's placental-derived cell therapy platform alongside existing antibody therapies to overcome obstacles such as antigen escape and tolerability issues associated with traditional cell therapies.

Celularity's approach involves a "universal receptor" strategy, where genetically modified T-cells expressing a proprietary CD16 are combined with approved antibodies to target a wide range of cancers and other conditions. The company continues to progress its pipeline, aiming to confront aging-related healthcare challenges beyond cancer, including cellular senescence.

Celularity is known for its innovative use of placental-derived cells, including mesenchymal-like adherent stromal cells (MLASCs), T-cells engineered with CAR (CAR T-cells), and both genetically modified and unmodified natural killer (NK) cells. These therapies are designed to address diseases associated with aging, such as degenerative diseases, cancer, and immune disorders.

While the company's announcement includes forward-looking statements about the potential of its therapies, actual results may differ due to various factors, including the inherent risks of biotechnological development. The information provided is based on a press release statement from Celularity Inc.

InvestingPro Insights

Celularity Inc. (NASDAQ: CELU) has recently shared promising data from their innovative T-cell therapy platform, highlighting their commitment to advancing regenerative medicine. While the scientific community watches their progress closely, investors are equally keen on understanding the financial health and future prospects of the company. Here are some InvestingPro Insights that shed light on Celularity's current financial situation:

InvestingPro Data indicates that Celularity has a market capitalization of $67.74 million, reflecting its size in the biotech industry. Despite the potential of their therapies, the company operates with a significant debt burden and is quickly burning through cash, with a reported operating income margin of -658.47% for the last twelve months as of Q1 2023. Moreover, the company's revenue has seen a decrease of 20.93% over the same period.

InvestingPro Tips suggest that analysts are anticipating sales growth in the current year, which could be a positive sign for the company's potential to rebound. Still, they do not expect the company to be profitable this year, and net income is projected to drop. These financial challenges are reflected in the company's stock performance, which has seen a significant hit over the last week, with a price total return of -10.12%.

For those considering investing in Celularity, it's important to note that the company does not pay a dividend to shareholders. For a deeper dive into Celularity's financial metrics and additional expert analysis, investors can explore InvestingPro, which offers over 10 additional tips on CELU. Use coupon code PRONEWS24 to get an additional 10% off a yearly or biyearly Pro and Pro+ subscription.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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