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Bernstein sees GLP-1 drugs revolutionizing the $95Bn global obesity market by 2030

EditorAhmed Abdulazez Abdulkadir
Published 12/13/2024, 09:54 PM
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On Friday, Bernstein analysts highlighted the significant role of GLP-1 medications in addressing the global obesity epidemic, with an emphasis on the current market dominance of Novo Nordisk (NYSE:NVO)'s Wegovy and Eli Lilly (NYSE:LLY)'s Zepbound. With a market capitalization of over $705 billion and impressive revenue growth of 27% in the last twelve months, Eli Lilly stands as a prominent player in this expanding market.

The global market for anti-obesity drugs is projected to reach $95 billion by 2030, with innovations in oral formulations and drugs aimed at preserving muscle mass driving the industry forward.Want deeper insights into Eli Lilly's market position? InvestingPro offers exclusive analysis and 15+ additional ProTips about the company's financial health and growth prospects.

The prevalence of overweight and obesity in the U.S. stands at 73%, with countries like Mexico, Australia, and the UK not far behind. The difficulty of weight loss is compounded by various factors, including lifestyle and biological challenges. GLP-1s, however, offer a promising new approach. Despite potential barriers such as insurance coverage, manufacturing capacity, and patient adherence, the market is evolving with new treatments in development.

It has been over a year since the SELECT trial data from Novo Nordisk brought attention to the potential of GLP-1 medications to revolutionize the fight against obesity. Although the initial excitement has settled, the long-term impact of these drugs is still considered significant. The development of next-generation GLP-1s, including oral options and treatments that maintain muscle mass, continues to be a focus in the pharmaceutical industry.

The pipeline for injectable anti-obesity drugs includes candidates from Novo Nordisk, Eli Lilly, and Boehringer Ingelheim, with oral formulations also being developed. Eli Lilly's strong financial position, evidenced by its impressive 80.91% gross profit margin and projected 34% revenue growth for FY2024, positions it well to capitalize on this market opportunity. However, adherence to these medications remains a challenge, with only 32% of Wegovy users continuing treatment after one year. Improving adherence may involve reframing obesity as a chronic condition and addressing issues such as food addiction.

In the U.S. healthcare sector, the growth of the GLP-1 market is seen as beneficial for pharmacy benefit managers and mildly positive for managed care organizations. While Eli Lilly trades at a relatively high P/E ratio of 84, suggesting premium pricing, InvestingPro's comprehensive analysis indicates the stock is slightly overvalued despite its strong market position. The impact on Medtech is mixed, with potential headwinds for dialysis providers in the long term, while other sectors may see changes in demand due to shifts in weight-related health issues and increased life expectancy.Access the full Pro Research Report and detailed financial analysis for Eli Lilly and 1,400+ other stocks on InvestingPro.

In other recent news, Eli Lilly, a global pharmaceutical firm, has made notable advancements in its clinical trials, financial strategies, and accessibility initiatives. The company recently announced a $15 billion share repurchase initiative and a 15% increase in its quarterly dividend, marking the seventh year of consecutive dividend growth.

In collaboration with digital health company Ro, Eli Lilly aims to streamline the process for patients to obtain Zepbound single-dose vials through LillyDirect, a self-pay pharmacy channel. This partnership aims to expand access to FDA-approved obesity treatments.

On the clinical front, Eli Lilly revealed promising results from the Phase 3 EMBER-3 study, evaluating the efficacy of imlunestrant, an investigational oral selective estrogen receptor degrader (SERD), for the treatment of advanced breast cancer. The study demonstrated a significant improvement in progression-free survival (PFS), both as monotherapy and in combination with the CDK4/6 inhibitor Verzenio.

Furthermore, Bernstein SocGen Group reaffirmed its positive stance on Eli Lilly, maintaining an Outperform rating, citing potential growth for the company and its GLP1 market. This comes amidst Robert F. Kennedy Jr.'s emphasis on lifestyle changes over GLP-1 drugs for weight management, causing investors to closely monitor his potential impact on health policy.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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