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Jacobio Pharmaceuticals Group Co., Ltd., a clinical-stage pharmaceutical company, focusing on the in-house discovery and development of oncology therapies. The company’s lead drug development programs include two clinical-stage allosteric Src homology region 2 domain-containing phosphatase-2 (SHP2) inhibitors comprising JAB-3312 and JAB-3068 for the treatment of esophageal cancer; JAB-8263, a small molecule inhibitor of BET family proteins regulating MYC transcription to treat various cancers; and JAB-21822, an oral small molecule targeting mutant KRAS G12C protein. It also develops JAB-BX102, a humanized inhibitory antibody against human CD73 for the treatment of PD-(L)1 resistant cancer; JAB-2485, an aurora A kinase inhibitor for solid tumors; JAB-24114, a tumor metabolic pathway for the treatment of solid tumors; and JAB-BX300, a molecule antibody targeting RAS pathway to treat pancreatic and other solid tumors with KRAS mutations. The company has a strategic collaboration with AbbVie Ireland Unlimited Company to develop and commercialize SHP2 inhibitors. The company was founded in 2015 and is headquartered in Beijing, China.
Name | Age | Since | Title |
---|---|---|---|
Ruilin Song | 59 | 2020 | Independent Non-Executive Director |
Yunyan Hu | 61 | 2018 | Executive VP & Executive Director |
Bai Lu | 65 | 2023 | Independent Non-Executive Director |
Xiaojie Wang | 59 | 2015 | Executive Director & President of Administration |
Yinxiang Wang | 58 | 2018 | Executive Chairman & CEO |
Ge Wu | 56 | 2020 | Independent Non-Executive Director |
Yanmin Tang | 51 | 2018 | Non-Executive Director |
Te-li Chen | 54 | 2020 | Non Executive Director |
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